Hi Preethi-
If the "mentor.calibre.2010.4.csh" means you have Calibre v2010.4, and the error message you get in the snapshot is from v2009.4, somewhere you are getting an incompatible license server.
Calibre updated the FlexLM software at v2010.1 -- you can't use the same license host for both 2010.4 and 2009.4. So first step is to find out if you really do have 2010.4 -- the script could be called that for some other reason. (The transcript header you posted is pretty clear that Calibre Interactive, at least, is v2009.4.)
Hopefully you have access to someone knowledgeable about the product trees you are using. If there really are multiple product versions installed (it isn't that uncommon), they'll be able to help you fix up either the Virtuoso call to Calibre or the LM_LICENSE_MANAGER setting.
Failing someone local & knowledgeable, the MGC customer support people get licensing questions frequently and can probably walk you through the investigation and any necessary changes.