Hi,
I guess the high-side is the name for the main MOSFET and the low-side is the diode replacement MOSFET
HO of the IR2110 is the gate for the High side Mosfet = positive side
LO of the IR2110 is the gate for the Low side Mosfet = positive side
VS_Boost (same as above) is for the high side, thus it must not be coonected to GND, but the half bridge output.
I don´t recommend 1k for the GS_resistors, they just drain out your bootstrap capacitor. Better use 10k.
When designing electronics you need to read the datasheets. The IC maunfacturer additionally provides design notes and application notes.
Whether your design works or not also highly depends on PCB layout. Don't try at all to do this on a breadboard.
Especially for the IR2110 there are - I guess - more than 1000 threads here. In case of problems: read through them.
Biggest problems: PCB layout, wrong signal levels, PCB layout, bootstrap problems, dead time problems .... did I already mention PCB layout? ;-)
Klaus