What values ​​are less likely to be confused between them

[Sink0]

Hi, i need to implement a communication where three commands (1 byte wide) wont carry a CRC number. Therefore i need to difine their representative numbers to be less likely to be confused between them. The bytes have no encoding during the data transmission. Any sugestions of which 8-bit patterns are less liked to be confused between them?

Thank you!

 

[ark5230]

Is it communication between two MCU's or what?
What sort of confusion is of concern?
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ARK

 

[Sink0]

The communication is between FPGAs, data is recovered using dephased clocks. 4 samples for each bit. Fixed frequency.

thank you!