Hi,
if you want to design a matching network without any data it will be almost imposible (you have to know at least something!). If you have small signal S parameters you can try starting from them and put some trimming pads in the layout to trim the performance in the large signal operation. Then you can take those trimmings into account and make a final layout.
If you really don't have anything to start with, the best way is to use tuners with the device and do a load pull measurements, but I assume this is not the option for you. You can get close to this by puting a transistor to a jig having only reasonably long 50Ohm lines at input and output and then play a bit with moving around and soldering down some copper tapes stubs to get close to the desired performance. Then you can simulate your trimmings and get the idea what device likes to see. Then you can design matching networks with trimming pads and repeat the cycle. This is very primitive and slow but it gives results!
flyhigh