It is the method I use. Tools: Eagle pcb because it has hpgl output. Plotter HP7475 slightly modificated to fit the pen. Pen is a Steadtler Lumocolor permanent 313.
Insert in the hpgl code VS1; for very low plotting speed.
See **broken link removed**
Dubblesided: difficult.
A long time ago I would use a HP pen plotter as a backup device if our Gerber photo plotter was down. I would plot at 2:1 scale with ink pens on mylar. I would add a reference line along the long side of the pcb image and add a tolerence of +-.005 inch. I would then take it to a technical photo-reproduction house which would reduce the image onto films. The films along with a paper punch drill file was sent to the manufacturer with good results. but this was in the days of the .100 dip with a single line between.