this time I generated a_ctrl and a_data[3:0] from sys_clk domain. Actually a_ctrl is used as clock to sync with a_data for other module to use. Can I check if there is skew between a_ctrl and a_data[3:0] with primetime ? Thx.
you can use data_check command in primetime to check signals which are not in the setup and hold format in the library. The data check commands are designed for the purposes of timing checks between handshaking systems.