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It depends very much on the level of design complexity. In case of a complex design you need an advanced constraint manager and always Mentor SI Hyperlynx supports Cadence designs too.
If you are doing a very basic design then any other tool like Altium, Pads will also be good. They are economical comparatively and capable of doing most designs.
I disagree, as well as hate these PCB packages comparisons.
I have used numerous packages in the past and have managed to lay boards out exactly the same on the follwoing packages:
and collegues here have done the same sort of boards on boardsataion.
So any package from the top four Cadence, Zuken, Mentor, Altium will allow you to do any board you want to design, the only difference will be user interface and cost, and here I am talking about high speed, constraint driven, FPGA's, DDR memory, gigabit ethernet blah blah blah. If you go down a technolgy step, then just about any PCB design package will allow you to join the dots.
The only way to determine what is best for yourself is to try the software.