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In general, from a physical point of view , as frequency increase as the guided wave media is preferred.
The technological progress continuosly move in advance the boundry, but it's unavoidable that the performances will be poor.
At present, 1.0 mm is the name of the expensive and fragile coax connector made by Agilent .
Connection discontinuity and repeatability are very better on WR10 rather than 1 mm coax.