80V is nothing. We did 200V parts with no special measures,
no increased pin spacing etc. However what works, and
what regulations laid down from above insist upon, are
two different constraints. Of course I wouldn't go 100V
on a 25-mil lead pitch if it was going to get damp, because
even 12V will start to corrode right quick if left powered
and wet (like a lovingly hand constructed test fixture of
mine, with 28V supply and active pins, worked fine for
the first round of testing but months later, was a mess
of green goo in the contactor; -55C testing condensed
water in spots where the purge fitting was not effective).