After synthesis , there is no information about the routing delay and hence clock tree information were not there. To take this delay in account, We declare clock uncertainty which will take care for clock skew + jitter.
During STA, we have information about clocks network and while calculating timing path, tool will calculate the clock delay along with data delay. the only thing need to take care in STA is jitter , that'why we give uncertainty for jitter in sta.
Rahul