Hi,
1) the advantane is highe efficiency. But with higher output voltage the possible benefit in efficiency becomes lower.
2) all that's important for you: Besides Rds-on, switching speeds, specified currents an voltages...cost, availability, package...
You may use the Mosfet in reverse, so that - at light loads - you may switch OFF gate control... while the internal body diode does the job. Check if the internal body diode is fast enough. But I expect it's not a problem, because at light loads you will be in DCM.
The current should be zero befor the low side Moset gets switched ON.
Klaus