if u want a balanced inverter with a normal skew 2/1 shud be good..as mobility ratios are between 2-3 ...u can use PN ratios for average delay as arnd 1.5....u can hold this ratio and decide the width of ur pmos and nmos based on output fanout/load...
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And...u can pick any logical effort info...and chk the same....
You need to simulate and get the results accurately. However the results will largely depend on the model cards that you are using, that is what decides the mobility ratio and hence the width ratio.
Strictly it would be wrong to quote any numbers here but you can take wp~2.5wn - not exact, only a rough idea).
You can do a hspice simulation with varying ratios and analyse the results on awaves. That should give you a rough idea of the ratio that you would need.
To be accurate, you'd better use spice to simulate the inverter with associated technology model. Roughly, the ratio is in 2-2.5. The mobility is not the only factor you need to consider , there are also some other factors: parasitic capacitance is one of them, which has different weight for different technology