what type of tools you want to install? some one you can do it, some one not.
i remember there are no problem just like $yn, pt & tm@x etc. but for hsp!ce, ap0llo, i don't think so.
maybe you better install them in a same root directory, just like /home/syn0psys, & separate them in different sub-directory, just like SYN, PT, HSPICE etc.
I think it also depends on which version you use. You know pt has pts (standalone) and pt. The former need you to install it standalone and the late one need you install it with syn tools.