Unfortunately, you need the resistors to balance the voltage across the caps. If you leave them off, and one cap has more leakage current across it than the other, then that cap will have 5 volts across it, and the other one 45 volts across it. This is a very common technique in high voltage power supplies.
In most RF applications, if the resistors are greater than 1K, they are relatively transparent to the RF signal.
Of course, this only works well when the 2 series caps are mounted in shunt. If you were trying to use the 2 series caps in series as a DC block, adding the resistors would of course negate the reason for the capacitor in the first place.