Hi,
K5, K6: AHC driven with 5V supply can not reliably work with 3.3V (supply) input levels.
--> power them with 3V3 (my recommendation) or use AHCT type logic.
K2: one output is active in either case. be sure to prevent short circuit. To be safe: either use the IOE input or install series resistors.
(IOE: a pullup and two schottky diodes: one cathod to PMWR the other to PMRD could work)
generally: don´t leave any (unused) input floating. Neither analog nor digital.
No need to RESET the floppy driver IC? A port pin may be used or you may connect it to the PIC_RESET.
Btw: PIC is 3V3 powered but RESET is 5V level. Is this O.K.?
Is it O.K. to leave VUSBV3 and VBUSON not connected?
K3 should work. ..But any AHCT buffer will do, too. Single 5V supplied.
And it´s swapped in direction (referred to K2). No problem, but not very nice, too.
Klaus