There are several advantages to using differential signaling. Three of the most important are these:
(1) Differential receivers reject common mode noise due to skew, power supply noise, interference, etc.
(2) Differential signals effectively double the voltage swing at the differential receiver increasing S/N.
(3) Well balanced and terminated differential transmission lines generate less EMI.
For these reasons, differential output formats are typically selected in high frequency and/or low jitter applications.
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