Hi,
it´s a rather general question. Usually not that suitable for a forum.
It´s better to ask a detailed question, so we can focus on it.
We won´t do all possible calculations and considerations for you. Tell us what informatin you are interested in.
Nowadays there are simualtions tools. Please use them on your own to see voltage, current, power dissipation of each part.
For a real circuit add a lot of margin regading V, I, P...
Safety: get familiar with safety regulations of your country. Especially creepage and clearance distance. Here the PCB layout plays a major role.
Klaus