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A negative gain for LNA suggest many things. First, your device may be blowned. This will cause your transistor to act more like a resistor at the gate-source region. I'm not sure which device you are using but, check the manufacturer datasheet to make sure that you're applying the proper temperature on the various pad when soldering your device (if you've done this yourself). Another thing you should check is to see whether the LNA is pulling the right DC voltages and currents at all terminals.
The circuit diagram you have uploaded is VERY cluttered and hard to read. Study the ADS help files for finding out how to avoid text overlap. One poster also asked for DC-voltages and currents. Do you have any control of these parameters? It's difficult to help you if you don't start by solving these issues.
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