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I have use PCB Software many years, so this is my opinion : for Smal and easy design U can use PowerPCB, Orcad, Protel. for Complex and hishspeed design U should use Cadence PSD14.xx or Mentor WG, and use Spectraquest or IXC to simulation. HP company use BoardStaion of Mentor, but it very complex to learn and use so U can use WG, it also power full for PCB design in Highspeed design field.
I recently installed Kicad (free). Schematic and PCB editor work very well. Easy to learn does up to 16 layers.
A little bit of work to collect libraries for components but now I have over 15,000 footprints at my disposal.
Good help files and component / symbol editors work good as well.
Would highly recommend if on a tight budget.