DC Blocks which you place in labaratory is actually real capacitors which you use in circuits to prevent unwanted signals from entering to either port(terminal) of your device. Those components will be replaced by real inductors and capacitors serving the same purpose in your circuit.
When you talk about realistic, things get much more complicated; because now you have to think more than just designing(ie. tolerances of components effect your design, heat compensation techniques, so on so forth)