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Many companies are using this for power estimating ans verification after synthesis. Nanosim is a package of many simulation tools from synopsis, and powermill is added. Powermill can work seamlessly with synopsis's VCS, except the Synopsis' waveviever, the waveform output file *.out can also be open by cadence's simvision.
The powermill have many accuracy class when run simulation. At the most accurate class, we can get the same result as HSPICE's. However, when simulate a netlist of a greate scale chip, we must think of the tradeoff between accuracy and simulation speed. Powermill have a mechanism that can choose the accuracy automatically at many normal conditions in order to control the simulation time is acceptible, of course it supports define the accuracy manually.