At the higher data rates I recommend you move to the
LVDS standard, for which there are CMOS<>LVDS chips
for almost any supply voltage you'd like (at least, from
1.8V through 5V). A transmitter at one end (say, 5V),
a 100-ohm differential wire pair and a receiver at the
other (say, 3.3V).
I have found in some ASIC designs that 80MHz with a
"5mA" CMOS driver and 10pF load is going to give pretty
poor (and PVT-variable) waveshape.
The data rate the atmega can operate at is 16 MHz , The 80 MHz is the max data rate the MAX3375 can handle, So the data rate that will operate is at 16 MHz