It makes no sense to include the DC voltage. It has no effect on the 2.4GHz results. These EM simulators do a linear analysis, where all frequencies can be analyzed separately.
If you think that the DC layout has an effect at 2.4GHz, include that layout and replace the "DC source" with the corresponding impedance at 2.4GHz (approximate short? approximate open?)
I don't know your circuit, but it's possibly some high impedance. In case of doubt, you can try both open and short and see if there is any difference.