Yes, as you get high enough you can get more than one mode of propagation. That usually makes the signal unusable (different modes have different propagation velocities). But there are some notable exceptions. You might be passing power into a multimode cavity for industrial heating, and the pressence of more than one mode is not a problem. You might be communicating down a big pipe (like a mine shaft) and even though there is a multimoding, you can still send ~low data rate info down the "waveguide". Stuff like that.