Normally relay contacts can handle AC better than DC. So the relay can drive 220V and perhaps 100-200mA (please check the details).
On the other hand, relays can be driven by AC or DC and that cannot be exchanged or interchanged. If the relay coils can support 5V DC, you cannot change it to 12V AC or even 5V AC.
Good relay contacts are made of gold, sliver, platinum or tungsten, depending on the current and voltage. Take a good look at the contacts and you will most likely be able to decide yourself whether the contacts can support high voltages / high currents.