When you set up your Optimization Goal in ADS you can define multiple Limit Lines for different ranges of the independant variable. If frequency (freq) is set as the independant variable then each of these limits could have a different goal and all would be optimized at once. For each limit line the frequency range can include multiple frequency steps from the simulation sweep or just a single frequency point as required. Weighting could be used to make any limit more significant in the total error function calculation if required. There are many example projects/workspaces shipped with ADS that demonstrate configuration of optimization. The attached picture shows an example configuration to optimize S11.