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But why don't use mirror symmetry and use repeat symmetry, what is the problem of that?
Do you know ... when Maloberti created that document?
The asymmetry between source & drain generation due to the necessary 7° ion implant to avoid channeling.
See p.9 of Maloberti's Analog CMOS Layout tutorial: View attachment 145121
I liked the idea of rotating 90 degrees