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Thanks for this, its the crux of it...the thing is, the "loop" through the wire and through the y cap across the isol barrier (transformer pri to sec) in 4 is a lesser area loop than the corresponding loop in 2...so it should be better regards EMC?No:4 seems correct but LOW Side ( PCB ) should be connected to Chassis/Enclosure instead of Insulated Wire.( this will create a EMI problem)
#4 might perform better, especially if proper feedthrough capacitors are used. Feedthroughs should help with any of the four configurations.