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CMOS is lousy, noiser but cheaper.
BJT is better in frequency reponse and quieter, but it requires base current, and might be expensive.
It is impossible to make it clear in just one or two paragrahs.
You got to use opamps. Otherwise, it would be difficult. By the way, if, one day, you figure out a circuit to do this without an opamp or circuits similar to opamp, please let me know.
Re: A/D converter question
Full scale means the maximun input the ADC can take from your signal source, which is set by the internal reference voltage.
PGA can be internal or external. It helps to make the signal size to fit the ADC full scale.
GEAR is a numerical method in computing an integral. Cadence provides different numerical integral solver for different application. For example, if you have a convergence problem with one method, say trapozoidal, you may try gear2.
Re: bsim3v3 parameters
lamda is process dependent. Of course, it depends on the channel length also. To get an approximation of lamda, you got to simulate the I-V curve of the transistor.
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